H2AFY2 antibody (Middle Region)
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- Target See all H2AFY2 Antibodies
- H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Guinea Pig, Rabbit, Horse, Cow, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This H2AFY2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PRIHPELLAK KRGTKGKSET ILSPPPEKRG RKATSGKKGG KKSKAAKPRT
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against H2AFY2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human H2AFY2
- Top Product
- Discover our top product H2AFY2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 372 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))
- Alternative Name
- H2AFY2 (H2AFY2 Products)
- Synonyms
- macroH2A2 antibody, RGD1561371 antibody, MGC69037 antibody, MGC130768 antibody, macroh2a2 antibody, im:6898017 antibody, wu:fa14g05 antibody, zgc:114051 antibody, H2AFY2 antibody, H2A histone family member Y2 antibody, H2A histone family, member Y2 antibody, H2A histone family member Y2 L homeolog antibody, core histone macro-H2A.2 antibody, H2AFY2 antibody, H2afy2 antibody, h2afy2.L antibody, h2afy2 antibody, LOC100224559 antibody, LOC100343925 antibody, LOC100456998 antibody, LOC489024 antibody, LOC100738475 antibody
- Background
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H2AFY2 is the variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H2AFY2 may be involved in stable X chromosome inactivation.
Alias Symbols: macroH2A2
Protein Interaction Partner: UBC, SUZ12, EED, WWP1, CBX5, DIDO1, SUMO1, HDGF, tat,
Protein Size: 372 - Molecular Weight
- 40 kDa
- Gene ID
- 55506
- NCBI Accession
- NM_018649, NP_061119
- UniProt
- Q9P0M6
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