CDCA7L antibody (Middle Region)
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- Target See all CDCA7L Antibodies
- CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CDCA7L antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PPCRGICNCS YCRKRDGRCA TGILIHLAKF YGYDNVKEYL ESLQKELVED
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 90%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against CDCA7L. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CDCA7L
- Top Product
- Discover our top product CDCA7L Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 420 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CDCA7L (Cell Division Cycle Associated 7-Like (CDCA7L))
- Alternative Name
- CDCA7L (CDCA7L Products)
- Synonyms
- ram2 antibody, MGC154777 antibody, BC006933 antibody, JPO2 antibody, R1 antibody, RAM2 antibody, RAPGEF5 antibody, cell division cycle associated 7 like antibody, cell division cycle associated 7 like L homeolog antibody, cell division cycle-associated 7-like protein antibody, CDCA7L antibody, cdca7l.L antibody, LOC100454683 antibody, Cdca7l antibody
- Background
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CDCA7L plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter.CDCA7L plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. CDCA7L is involved in apoptotic signaling pathways. CDCA7L may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
Alias Symbols: DKFZp762L0311, JPO2, R1, RAM2
Protein Interaction Partner: KRTAP10-7, TRIM42, MORN3, BEND7, FAM9B, DEDD2, SSX2IP, ING5, TRAF3IP3, CEP70, CCDC33, CARD9, PRDM14, ZNF250, UTP3, CTNNBL1, ZNF821, CDCA7L, TFPT, ABT1, PRPF31, PPP1R16B, EIF4A3, STX11, UBL4A, TADA2A, NOP2, MFAP1, MDFI, LMO1, DAXX, BYSL, ANKRD11, SUV39H1,
Protein Size: 420 - Molecular Weight
- 46 kDa
- Gene ID
- 55536
- NCBI Accession
- NM_001127370, NP_001120842
- UniProt
- B3KTR5
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