ACTR3B antibody (N-Term)

Catalog No. ABIN2787218

This Rabbit Polyclonal antibody specifically detects ACTR3B in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio), Horse, Rabbit and Saccharomyces cerevisiae.

Quick Overview for ACTR3B antibody (N-Term) (ABIN2787218)

Target: ACTR3B (ARP3 Actin-Related Protein 3 Homolog B (ACTR3B))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio), Horse, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACTR3B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ACTR3B Antibody

Binding Specificity: N-Term

Sequence: MAGSLPPCVV DCGTGYTKLG YAGNTEPQFI IPSCIAIRES AKVVDQAQRR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against ACTR3B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ACTR3B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 418 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ACTR3B

Target: ACTR3B (ARP3 Actin-Related Protein 3 Homolog B (ACTR3B))

Alternative Name: ACTR3B

Background: ACTR3B plays a role in the organization of the actin cytoskeleton.ACTR3B may function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. ACTR3B may decrease the metastatic potential of tumors.
Alias Symbols: ARP11, ARP3BETA, DKFZp686O24114
Protein Interaction Partner: PAN2, EXOC5, UBC, RSRC1, ARPC3P1, ARPC5L, CCAR2, TWF2, ARPC1A, ARPC2, ACTR2, ARPC1B, ARPC3, ARPC4, ARPC5, CDK4,
Protein Size: 418

Molecular Weight: 47 kDa

Gene ID: 57180

NCBI Accession: NM_020445, NP_065178

UniProt: Q9P1U1

Pathways: Regulation of Actin Filament Polymerization