TBC1D24 antibody (Middle Region)

Catalog No. ABIN2787224

There is 1 publication for this product available. The Rabbit Polyclonal anti-TBC1D24 antibody is suitable to detect TBC1D24 in samples from Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog and Rabbit. It has been validated for WB.

Quick Overview for TBC1D24 antibody (Middle Region) (ABIN2787224)

Target: TBC1D24 (TBC1 Domain Family, Member 24 (TBC1D24))

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBC1D24 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TBC1D24 Antibody

Binding Specificity: Middle Region

Purpose: TBC1D24 Antibody - middle region

Sequence: SDPADRLSPF LAARHFNLPS KTESMFMAGG SDCLIVGGGG GQALYIDGDL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TBC1D24. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBC1D24

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57438-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-TBC1D24 antibody (ABIN2787224)

Lozano, Herman, Rothfuss, Rieger, Bayrak-Toydemir, Aprile, Fruscione, Zara, Fassio: "Clinical intrafamilial variability in lethal familial neonatal seizure disorder caused by TBC1D24 mutations." in: American journal of medical genetics. Part A, Vol. 170, Issue 12, pp. 3207-3214, (2016) (PubMed).

Target Details for TBC1D24

Target: TBC1D24 (TBC1 Domain Family, Member 24 (TBC1D24))

Alternative Name: TBC1D24

Background:

Background Information: TBC1D24 may act as a GTPase-activating protein for Rab family protein(s).

Gene Name: TBC1 domain family, member 24

Alternative Symbols: FIME, DEE16, DOORS, TLDC6, DFNA65, DFNB86, EIEE16, EPRPDC

Protein Name: TBC1 domain family member 24

Molecular Weight: 62kDa

Gene ID: 57465

NCBI Accession: NP_065756

UniProt: Q9ULP9