IPPK antibody (Middle Region)

Catalog No. ABIN2787322

Product Details anti-IPPK Antibody

Target: IPPK (Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase (IPPK))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IPPK antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KTLQVQMLDL LDIEGLYPLY NRVERYLEEF PEERKTLQID GPYDEAFYQK

Predicted Reactivity: Cow: 100%, Dog: 79%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against IPPK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IPPK

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 491 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IPPK

Target: IPPK (Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase (IPPK))

Alternative Name: IPPK (IPPK Products)

Synonyms: IPPK antibody, MGC146756 antibody, C9orf12 antibody, INSP5K2 antibody, IP5K antibody, IPK1 antibody, bA476B13.1 antibody, 1810043M15Rik antibody, InsP6 antibody, RGD1311271 antibody, rIpk1 antibody, ipk1 antibody, ipk1l antibody, si:dkey-42i9.3 antibody, zgc:110769 antibody, ATIPK1 antibody, M40H3 antibody, MJB21.19 antibody, MJB21_19 antibody, inositol-pentakisphosphate 2-kinase 1 antibody, inositol-pentakisphosphate 2-kinase antibody, inositol 1,3,4,5,6-pentakisphosphate 2-kinase antibody, inositol pentakisphosphate 2-kinase antibody, inositol-pentakisphosphate 2-kinase 1 antibody, IPPK antibody, LOC521083 antibody, ippk antibody, Ippk antibody, IPK1 antibody

Background: IPPK phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It also protects cells from TNF-alpha-induced apoptosis.
Alias Symbols: C9orf12, FLJ13163, INSP5K2, KIAA0699, bA476B13.1, IP5K, IPK1
Protein Interaction Partner: CDK12, UBC,
Protein Size: 491

Molecular Weight: 56 kDa

Gene ID: 64768

NCBI Accession: NM_022755, NP_073592

UniProt: Q9H8X2