IPPK antibody (Middle Region)

Catalog No. ABIN2787322

The Rabbit Polyclonal anti-IPPK antibody is suitable to detect IPPK in samples from Human, Mouse, Rat, Dog, Horse, Cow, Rabbit, Guinea Pig and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for IPPK antibody (Middle Region) (ABIN2787322)

Target: IPPK (Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase (IPPK))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IPPK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IPPK Antibody

Binding Specificity: Middle Region

Purpose: IPPK Antibody - middle region

Sequence: KTLQVQMLDL LDIEGLYPLY NRVERYLEEF PEERKTLQID GPYDEAFYQK

Predicted Reactivity: Cow: 100%, Dog: 79%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against IPPK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IPPK

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57655-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for IPPK

Target: IPPK (Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase (IPPK))

Alternative Name: IPPK

Background:

Background Information: IPPK phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It also protects cells from TNF-alpha-induced apoptosis.

Gene Name: Inositol 1,3,4,5,6-pentakisphosphate 2-kinase

Alternative Symbols: IP5K, IPK1, C9orf12, INSP5K2, bA476B13.1

Protein Name: Inositol-pentakisphosphate 2-kinase

Molecular Weight: 56kDa

Gene ID: 64768

NCBI Accession: NP_073592

UniProt: Q9H8X2