PDYN antibody (Middle Region)

Catalog No. ABIN2787326

The Rabbit Polyclonal anti-PDYN antibody (ABIN2787326) specifically detects PDYN in WB. The antibody is reactive with Human, Rat, Mouse, Guinea Pig, Cow, Dog, Goat, Horse, Rabbit, Zebrafish (Danio rerio) and Sheep samples.

Quick Overview for PDYN antibody (Middle Region) (ABIN2787326)

Target: PDYN (Prodynorphin (PDYN))

Reactivity: Human, Rat, Mouse, Guinea Pig, Cow, Dog, Goat, Horse, Rabbit, Zebrafish (Danio rerio), Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDYN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDYN Antibody

Binding Specificity: Middle Region

Purpose: PDYN Antibody - middle region

Sequence: SELMRDAQLN DGAMETGTLY LAEEDPKEQV KRYGGFLRKY PKRSSEVAGE

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against PDYN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PDYN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57661-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDYN

Target: PDYN (Prodynorphin (PDYN))

Alternative Name: PDYN

Background:

Background Information: The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene Name: Prodynorphin

Alternative Symbols: ADCA, PENKB, SCA23

Protein Name: Proenkephalin-B

Molecular Weight: 27kDa

Gene ID: 5173

NCBI Accession: NP_077722

UniProt: P01213