CARD9 antibody (Middle Region)

Catalog No. ABIN2787348

This Rabbit Polyclonal antibody specifically detects CARD9 in WB. It exhibits reactivity toward Human, Mouse, Horse and Dog.

Quick Overview for CARD9 antibody (Middle Region) (ABIN2787348)

Target: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Reactivity: Human, Mouse, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARD9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CARD9 Antibody

Binding Specificity: Middle Region

Purpose: CARD9 Antibody - middle region

Sequence: ALHQEQVLRN PHDAGLSSGE PPEKERRRLK ESFENYRRKR ALRKMQKGWR

Predicted Reactivity: Dog: 92%, Horse: 86%, Human: 100%, Mouse: 90%

Characteristics: This is a rabbit polyclonal antibody against CARD9. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CARD9

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57704-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CARD9

Target: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Alternative Name: CARD9

Background:

Background Information: The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.

Gene Name: Caspase recruitment domain family, member 9

Alternative Symbols: CANDF2, hCARD9

Protein Name: Caspase recruitment domain-containing protein 9

Molecular Weight: 62kDa

Gene ID: 64170

NCBI Accession: NP_434700

UniProt: Q9H257

Pathways: Activation of Innate immune Response