ATP6V1G2 antibody (Middle Region)

Catalog No. ABIN2787359

The Rabbit Polyclonal anti-ATP6V1G2 antibody is suitable to detect ATP6V1G2 in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Pig, Rabbit and Sheep. It has been validated for WB.

Quick Overview for ATP6V1G2 antibody (Middle Region) (ABIN2787359)

Target: ATP6V1G2 (ATPase, H+ Transporting, Lysosomal 13kDa, V1 Subunit G2 (ATP6V1G2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Pig, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V1G2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATP6V1G2 Antibody

Binding Specificity: Middle Region

Sequence: NLSAEVEQAT RRQVQGMQSS QQRNRERVLA QLLGMVCDVR PQVHPNYRIS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 100%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against ATP6V1G2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATP6V1G2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 118 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATP6V1G2

Target: ATP6V1G2 (ATPase, H+ Transporting, Lysosomal 13kDa, V1 Subunit G2 (ATP6V1G2))

Alternative Name: ATP6V1G2

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. This gene had previous gene symbols of ATP6G and ATP6G2. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: ATP6G, ATP6G2, NG38, VMA10
Protein Interaction Partner: UBC, IQCB1, ATP6V1E1,
Protein Size: 118

Molecular Weight: 13 kDa

Gene ID: 534

NCBI Accession: NM_130463, NP_569730

UniProt: O95670

Pathways: Transition Metal Ion Homeostasis, Proton Transport