PPP2R5D antibody (Middle Region)

Catalog No. ABIN2787385

The Rabbit Polyclonal anti-PPP2R5D antibody is suitable to detect PPP2R5D in samples from Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for PPP2R5D antibody (Middle Region) (ABIN2787385)

Target: PPP2R5D (Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R5D antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPP2R5D Antibody

Binding Specificity: Middle Region

Sequence: ETEAVQMLKD IKKEKVLLRR KSELPQDVYT IKALEAHKRA EEFLTASQEA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PPP2R5D. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PPP2R5D

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 602 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP2R5D

Target: PPP2R5D (Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D))

Alternative Name: PPP2R5D

Background: The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: B56D, MGC2134, MGC8949
Protein Interaction Partner: FSD2, USHBP1, PPP2R1A, UBC, NIF3L1, GOPC, SH3GLB1, HECTD1, ARPC2, ARPC1B, TPD52L2, PRDX2, RPA2, RANGAP1, PRDX1, LPP, FEN1, DHPS, YWHAB, SOX2, Dlg4, PPP2R1B, GSK3B, CHEK2, SUMO2, Sgol1, PPP4C, PPP2CB, PPP2CA, PPFIA1, HAND2, HAND1, ARL2, NEK1,
Protein Size: 602

Molecular Weight: 70 kDa

Gene ID: 5528

NCBI Accession: NM_006245, NP_006236

UniProt: Q14738

Pathways: PI3K-Akt Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades