PRKAR1A antibody (N-Term)

Catalog No. ABIN2787417

The Rabbit Polyclonal anti-PRKAR1A antibody is suitable to detect PRKAR1A in samples from Human, Rat, Mouse, Cow, Sheep, Guinea Pig, Rabbit, Dog, Horse and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for PRKAR1A antibody (N-Term) (ABIN2787417)

Target: PRKAR1A (Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A))

Reactivity: Human, Rat, Mouse, Cow, Sheep, Guinea Pig, Rabbit, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKAR1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRKAR1A Antibody

Binding Specificity: N-Term

Sequence: REYFERLEKE EARQIQSLQK SGIRTDSRED EISPPPPNPV VKGRRRRGAI

Predicted Reactivity: Cow: 86%, Dog: 79%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 86%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against Prkar1a. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Prkar1a

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 381 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRKAR1A

Target: PRKAR1A (Protein Kinase, CAMP-Dependent, Regulatory, Type I, alpha (Tissue Specific Extinguisher 1) (PRKAR1A))

Alternative Name: Prkar1a

Background: Prkar1a is a regulatory subunit of cAMP-dependent protein kinase (PKA), negatively regulates meiosis .
Alias Symbols: RIIA
Protein Size: 381

Molecular Weight: 41 kDa

Gene ID: 25725

NCBI Accession: NM_013181, NP_037313

UniProt: P09456

Pathways: Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma