TAF1C antibody (N-Term)

Catalog No. ABIN2787455

The Rabbit Polyclonal anti-TAF1C antibody is suitable to detect TAF1C in samples from Human, Mouse, Rat, Guinea Pig, Dog, Cow and Horse. It has been validated for WB.

Quick Overview for TAF1C antibody (N-Term) (ABIN2787455)

Target: TAF1C (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa (TAF1C))

Reactivity: Human, Mouse, Rat, Guinea Pig, Dog, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF1C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TAF1C Antibody

Binding Specificity: N-Term

Sequence: MDFPSSLRPA LFLTGPLGLS DVPDLSFMCS WRDALTLPEA QPQNSENGAL

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 77%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TAF1C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TAF1C

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 869 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TAF1C

Target: TAF1C (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa (TAF1C))

Alternative Name: TAF1C

Background: Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1C is the largest SL1-specific TAF. Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.
Alias Symbols: MGC:39976, SL1, TAFI110, TAFI95
Protein Interaction Partner: UBC, Tbp, Taf1b, Taf1a, UFD1L, TTR, TK1, SMN1, H2AFX, TAF12, TAF1D, POLR1E, RRN3, TRIM24, TP53, UBTF, CD3EAP, MYC,
Protein Size: 869

Molecular Weight: 95 kDa

Gene ID: 9013

NCBI Accession: NM_005679, NP_005670

UniProt: Q15572