PREB antibody (N-Term)

Catalog No. ABIN2787462

The Rabbit Polyclonal anti-PREB antibody (ABIN2787462) specifically detects PREB in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig and Zebrafish (Danio rerio) samples.

Quick Overview for PREB antibody (N-Term) (ABIN2787462)

Target: PREB (Prolactin Regulatory Element Binding (PREB))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PREB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PREB Antibody

Binding Specificity: N-Term

Purpose: Preb Antibody - N-terminal region

Sequence: RRRGVELYRA PFPLYALRID PKTGLLIAAG GGGAAKTGIK NGVHFLQLEL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against Preb. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Preb

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57930-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PREB

Target: PREB (Prolactin Regulatory Element Binding (PREB))

Alternative Name: Preb

Background:

Background Information: Preb was first identified based on its probable role in the regulation of pituitary gene transcription. It binds to the prolactin gene (PRL) promoter and seems to activate transcription. Guanine nucleotide exchange factor that activates SARA2. It is also required for the formation of COPII transport vesicles from the ER.

Gene Name: prolactin regulatory element binding

Alternative Symbols: C85705

Protein Name: Prolactin regulatory element-binding protein

Molecular Weight: 45kDa

Gene ID: 50907

NCBI Accession: NP_057912

UniProt: Q9WUQ2

Pathways: ER-Nucleus Signaling