CEBPB antibody (N-Term)

Catalog No. ABIN2787467

The Rabbit Polyclonal anti-CEBPB antibody (ABIN2787467) specifically detects CEBPB in WB. The antibody is reactive with Human, Rat, Pig, Cow, Dog and Rabbit samples.

Quick Overview for CEBPB antibody (N-Term) (ABIN2787467)

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Reactivity: Human, Rat, Pig, Cow, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEBPB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CEBPB Antibody

Binding Specificity: N-Term

Purpose: CEBPB Antibody - N-terminal region

Sequence: AIDFSPYLEP LGAPQAPAPA TATDTFEAAP PAPAPAPASS GQHHDFLSDL

Predicted Reactivity: Cow: 86%, Dog: 92%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against CEBPB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CEBPB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57940-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CEBPB

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Alternative Name: CEBPB

Background:

Background Information: CEBPB is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: CCAAT/enhancer binding protein (C/EBP), beta

Alternative Symbols: TCF5, IL6DBP, NF-IL6, C/EBP-beta

Protein Name: CCAAT/enhancer-binding protein beta

Molecular Weight: 36kDa

Gene ID: 1051

NCBI Accession: NP_005185

UniProt: P17676

Pathways: Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation