POU2F3 antibody (C-Term)

Catalog No. ABIN2787499

This Rabbit Polyclonal antibody specifically detects POU2F3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Guinea Pig, Sheep, Cow and Horse.

Quick Overview for POU2F3 antibody (C-Term) (ABIN2787499)

Target: POU2F3 (POU Class 2 Homeobox 3 (POU2F3))

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Sheep, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POU2F3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-POU2F3 Antibody

Binding Specificity: C-Term

Purpose: POU2F3 Antibody - C-terminal region

Sequence: LSVPPVHSTM PGTVTSSCSP GNNSRPSSPG SGLHASSPTA SQNNSKAAVN

Predicted Reactivity: Cow: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against POU2F3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human POU2F3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57992-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for POU2F3

Target: POU2F3 (POU Class 2 Homeobox 3 (POU2F3))

Alternative Name: POU2F3

Background:

Background Information: This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: POU class 2 homeobox 3

Alternative Symbols: PLA1, OCT11, PLA-1, Epoc-1, OCT-11, OTF-11, Skn-1a

Protein Name: POU domain, class 2, transcription factor 3

Molecular Weight: 24kDa

Gene ID: 25833

NCBI Accession: NP_001231611

UniProt: Q9UKI9