GTF2B antibody (C-Term)

Catalog No. ABIN2787507

Product Details anti-GTF2B Antibody

Target: GTF2B (General Transcription Factor IIB (GTF2B))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Horse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF2B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SVAAAAIYMA SQASAEKRTQ KEIGDIAGVA DVTIRQSYRL IYPRAPDLFP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against GTF2B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GTF2B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 316 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GTF2B

Target: GTF2B (General Transcription Factor IIB (GTF2B))

Alternative Name: GTF2B (GTF2B Products)

Synonyms: CG5193 antibody, Dmel\\CG5193 antibody, TFIIB antibody, Tfiib antibody, TfllB antibody, dTFIIB antibody, dTfIIB antibody, dmTFIIB antibody, gtf2b antibody, tf2b antibody, tfiib antibody, XLTFIIB antibody, TF2B antibody, wu:fc44c11 antibody, zgc:66258 antibody, Transcription factor IIB antibody, transcription initiation factor iib antibody, transcription initiation factor IIB antibody, transcription initiation factor IIB 2 antibody, Transcription initiation factor IIB antibody, general transcription factor 2B S homeolog antibody, general transcription factor 2B L homeolog antibody, general transcription factor IIB antibody, TfIIB antibody, CNF01950 antibody, tfb antibody, CC1G_14689 antibody, HacjB3_18813 antibody, HALXA_RS07110 antibody, HALXA_RS16310 antibody, tf2b antibody, LOC100283348 antibody, gtf2b.S antibody, gtf2b.L antibody, GTF2B antibody, gtf2b antibody, Gtf2b antibody

Background: GTF2B is the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TF2B, TFIIB
Protein Interaction Partner: DRAP1, TNIP1, UBC, FBXO25, HNF4A, TCEA1, GTF2F2, GTF2F1, DEPDC7, SLC22A2, RELA, POLR2C, JAK3, HMGCL, SMURF1, THRA, TBP, POLR2E, SRA1, LSM4, LSM5, CIITA, NXF1, POU3F2, EP300, PSMA3, POLR2J, ESR1, UL48, NR1D2, NCOR1, TAF9, REST, tat, SAP25, MKX, CTDP1, POLR
Protein Size: 316

Molecular Weight: 35 kDa

Gene ID: 2959

NCBI Accession: NM_001514, NP_001505

UniProt: Q00403