HOXB3 antibody (N-Term)

Catalog No. ABIN2787515

The Rabbit Polyclonal anti-HOXB3 antibody is suitable to detect HOXB3 in samples from Human, Mouse, Rat, Cow, Rabbit, Horse, Dog, Pig and Guinea Pig. It has been validated for WB.

Quick Overview for HOXB3 antibody (N-Term) (ABIN2787515)

Target: HOXB3 (Homeobox B3 (HOXB3))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Horse, Dog, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXB3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HOXB3 Antibody

Binding Specificity: N-Term

Purpose: HOXB3 Antibody - N-terminal region

Sequence: SCMRPGLAPE PLSAPPGSPP PSAAPTSATS NSSNGGGPSK SGPPKCGPGT

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against HOXB3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXB3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58020-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HOXB3

Target: HOXB3 (Homeobox B3 (HOXB3))

Alternative Name: HOXB3

Background:

Background Information: HOXB3 belongs to ANTP homeobox family. It is a nuclear protein with a homeobox DNA-binding domain. HOXB3 gene is included in a cluster of homeobox B genes located on chromosome 17. The protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML).This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Homeobox B3

Alternative Symbols: HOX2, HOX2G, Hox-2.7

Protein Name: Homeobox protein Hox-B3

Molecular Weight: 44kDa

Gene ID: 3213

NCBI Accession: NP_002137

UniProt: P14651