JMJD5 antibody (Middle Region)

Catalog No. ABIN2787556

Product Details anti-JMJD5 Antibody

Target: JMJD5 (Jumonji Domain Containing 5 (JMJD5))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JMJD5 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Sequence: KYRPIQTPSV CSDSLESPDE DMGSDSDVTT ESGSSPSHSP EERQDPGSAP

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against JMJD5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human JMJD5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 416 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for JMJD5

Target: JMJD5 (Jumonji Domain Containing 5 (JMJD5))

Alternative Name: JMJD5 (JMJD5 Products)

Synonyms: jmjd5 antibody, JMJD5 antibody, 3110005O21Rik antibody, Jmjd5 antibody, zgc:173863 antibody, zgc:91962 antibody, RGD1304823 antibody, lysine demethylase 8 antibody, jumonji domain containing 5 antibody, hypothetical protein antibody, lysine (K)-specific demethylase 8 antibody, KDM8 antibody, PTRG_02386 antibody, MCYG_00400 antibody, CC1G_13927 antibody, PGTG_16928 antibody, kdm8 antibody, Kdm8 antibody

Background: JMJD5 is a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential role for this protein as a tumor suppressor.JMJD5 is a putative histone lysine demethylase that contains a Jumonji C (JmjC) domain (Shi, 2007 [PubMed 17909537]).[supplied by OMIM].
Alias Symbols: FLJ13798, JMJD5
Protein Interaction Partner: PCYT2,
Protein Size: 416

Molecular Weight: 47 kDa

Gene ID: 79831

NCBI Accession: NM_024773, NP_079049

UniProt: Q8N371

Pathways: Chromatin Binding