JMJD5 antibody (Middle Region)

Catalog No. ABIN2787556

This Rabbit Polyclonal antibody specifically detects JMJD5 in WB and ChIP. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Dog and Rabbit.

Quick Overview for JMJD5 antibody (Middle Region) (ABIN2787556)

Target: JMJD5 (Jumonji Domain Containing 5 (JMJD5))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JMJD5 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Product Details anti-JMJD5 Antibody

Binding Specificity: Middle Region

Purpose: JMJD5 Antibody - middle region

Sequence: LKQDISIPDY CSLGDGEEEE ITINAWFGPQ GTISPLHQDP QQNFLVQVMG

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against JMJD5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human JMJD5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58120-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for JMJD5

Target: JMJD5 (Jumonji Domain Containing 5 (JMJD5))

Alternative Name: JMJD5

Background:

Background Information: JMJD5 is a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential role for this protein as a tumor suppressor.JMJD5 is a putative histone lysine demethylase that contains a Jumonji C (JmjC) domain (Shi, 2007 [PubMed 17909537]).[supplied by OMIM].

Gene Name: Lysine (K)-specific demethylase 8

Alternative Symbols: JMJD5

Protein Name: Lysine-specific demethylase 8

Molecular Weight: 47kDa

Gene ID: 79831

NCBI Accession: NP_079049

UniProt: Q8N371

Pathways: Chromatin Binding