A2BP1 antibody (Middle Region)

Catalog No. ABIN2787590

Product Details anti-A2BP1 Antibody

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Cow, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This A2BP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TAAAYSDRNQ FVFVAADEIS CNTSAVTDEF MLPTPTTTHL LQPPPTALVP

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against A2BP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human A2BP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 395 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for A2BP1

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Alternative Name: A2BP1 (A2BP1 Products)

Background: Ataxin-2 binding protein 1(A2BP1) has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Four alternatively spliced transcript variants have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.
Alias Symbols: FOX1, HRNBP1, 2BP1, A2BP1, FOX-1
Protein Interaction Partner: C1orf94, RBPMS, PRR20A, HSFY1, RHOXF2, ALG13, RBFOX1, FAM168A, DAZAP2, MAGED1, BHLHE40, SNRPN, DAB1, CRX, UBC, HSFX1, RBM24, LZTS2, DMRTB1, PCBP4, NOC2L, GCA, RBFOX2, KIFAP3, CELF3, PSMF1, QKI, NUMBL, PRRC2A, ATXN2, ATXN1, HNRNPF, DVL2, ATN1, TNIP1,
Protein Size: 395

Molecular Weight: 42 kDa

Gene ID: 54715

NCBI Accession: NM_145893, NP_665900

UniProt: Q9NWB1