DAP Kinase 1 antibody (N-Term)

Catalog No. ABIN2787598

The Rabbit Polyclonal anti-DAP Kinase 1 antibody has been validated for WB. It is suitable to detect DAP Kinase 1 in samples from Human, Mouse, Rat, Dog, Guinea Pig and Rabbit.

Quick Overview for DAP Kinase 1 antibody (N-Term) (ABIN2787598)

Target: DAP Kinase 1 (DAPK1) (Death-Associated Protein Kinase 1 (DAPK1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAP Kinase 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DAP Kinase 1 Antibody

Binding Specificity: N-Term

Sequence: MTVFRQENVD DYYDTGEELG SGQFAVVKKC REKSTGLQYA AKFIKKRRTK

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DAPK1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DAPK1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1431 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DAP Kinase 1

Target: DAP Kinase 1 (DAPK1) (Death-Associated Protein Kinase 1 (DAPK1))

Alternative Name: DAPK1

Background: Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consen
Alias Symbols: DAPK, DKFZp781I035
Protein Interaction Partner: PDCD6, BECN1, DAPK1, UBC, MYL12B, MAPK3, MAPK1, CALM1, LRRK2, LRRK1, MDM2, LNX1, MIB1, FADD, KLHL20, CUL3, IKBKG, UNC5B, UNC5C, TRADD, YWHAB, TNFRSF1A, STX1A, CCNDBP1, TP53, ST13, HSP90AA1, YWHAQ, KRIT1, UNC5A,
Protein Size: 1431

Molecular Weight: 157 kDa

Gene ID: 1612

NCBI Accession: NM_004938, NP_004929

UniProt: P53355

Pathways: MAPK Signaling, Interferon-gamma Pathway