PHLDA2 antibody (N-Term)

Catalog No. ABIN2787606

The Rabbit Polyclonal anti-PHLDA2 antibody (ABIN2787606) specifically detects PHLDA2 in WB. The antibody is reactive with Human, Rat, Horse, Cow and Guinea Pig samples.

Quick Overview for PHLDA2 antibody (N-Term) (ABIN2787606)

Target: PHLDA2 (Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2))

Reactivity: Human, Rat, Horse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHLDA2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PHLDA2 Antibody

Binding Specificity: N-Term

Purpose: PHLDA2 Antibody - N-terminal region

Sequence: MKSPDEVLRE GELEKRSDSL FQLWKKKRGV LTSDRLSLFP ASPRARPKEL

Predicted Reactivity: Cow: 92%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Rat: 90%

Characteristics: This is a rabbit polyclonal antibody against PHLDA2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58238-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PHLDA2

Target: PHLDA2 (Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2))

Alternative Name: PHLDA2

Background:

Background Information: This gene is one of several genes in the imprinted gene domain of 11p15.5 which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Studies of the mouse gene, however, which is also located in an imprinted gene domain, have shown that the product of this gene regulates placental growth.

Gene Name: Pleckstrin homology-like domain, family A, member 2

Alternative Symbols: IPL, BRW1C, BWR1C, HLDA2, TSSC3

Protein Name: Pleckstrin homology-like domain family A member 2

Molecular Weight: 17kDa

Gene ID: 7262

NCBI Accession: NP_003302

UniProt: Q53GA4

Pathways: Regulation of Carbohydrate Metabolic Process