ACD antibody (C-Term)

Catalog No. ABIN2787610

The Rabbit Polyclonal anti-ACD antibody (ABIN2787610) specifically detects ACD in WB. The antibody is reactive with Human samples.

Quick Overview for ACD antibody (C-Term) (ABIN2787610)

Target: ACD (Adrenocortical Dysplasia Homolog (ACD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACD antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ACD Antibody

Binding Specificity: C-Term

Purpose: ACD Antibody - C-terminal region

Sequence: SSQPSPAICS APATLTPRSP HASRTPSSPL QSCTPSLSPR SHVPSPHQAL

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against ACD. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ACD

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58254-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ACD

Target: ACD (Adrenocortical Dysplasia Homolog (ACD))

Alternative Name: ACD

Background:

Background Information: ACD is a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere.This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.

Gene Name: Adrenocortical dysplasia homolog (mouse)

Alternative Symbols: PIP1, PTOP, TPP1, TINT1

Protein Name: Adrenocortical dysplasia protein homolog

Molecular Weight: 58kDa

Gene ID: 65057

NCBI Accession: NP_001075955

UniProt: Q96AP0

Pathways: Telomere Maintenance