ERCC4 antibody (Middle Region)

Catalog No. ABIN2787618

The Rabbit Polyclonal anti-ERCC4 antibody (ABIN2787618) specifically detects ERCC4 in WB. The antibody is reactive with Human, Rat, Dog and Horse samples.

Quick Overview for ERCC4 antibody (Middle Region) (ABIN2787618)

Target: ERCC4 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4))

Reactivity: Human, Rat, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERCC4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ERCC4 Antibody

Binding Specificity: Middle Region

Sequence: FLLRLYRKTF EKDSKAEEVW MKFRKEDSSK RIRKSHKRPK DPQNKERAST

Predicted Reactivity: Dog: 83%, Horse: 85%, Human: 100%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against ERCC4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ERCC4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 916 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ERCC4

Target: ERCC4 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4))

Alternative Name: ERCC4

Background: The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause
Alias Symbols: RAD1, XPF, ERCC11
Protein Interaction Partner: vpr, SLX4, UBC, MSH2, ERCC1, ALYREF, VPS26A, UBE2B, SLX1A, POLR2A, SUMO2, GTF2H1, SPTAN1, ERCC6, TADA2A, FANCG, PLK1, SLX4IP, SLX1B, RAD52, SPTA1, FANCA,
Protein Size: 916

Molecular Weight: 101 kDa

Gene ID: 2072

NCBI Accession: NM_005236, NP_005227

UniProt: Q92889

Pathways: DNA Damage Repair