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TNKS1BP1 antibody (Middle Region)

TNKS1BP1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2787645
  • Target See all TNKS1BP1 Antibodies
    TNKS1BP1 (Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))
    Binding Specificity
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 30
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 29
    • 1
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNKS1BP1 antibody is un-conjugated
    Application
    • 18
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Sequence
    DGEASQTEDV DGTWGSSAAR WSDQGPAQTS RRPSQGPPAR SPSQDFSFIE
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against TNKS1BP1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human TNKS1BP1
    Top Product
    Discover our top product TNKS1BP1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1729 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TNKS1BP1 (Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))
    Alternative Name
    TNKS1BP1 (TNKS1BP1 Products)
    Synonyms
    TAB182 antibody, Tab182 antibody, mKIAA1741 antibody, tankyrase 1 binding protein 1 antibody, 182 kDa tankyrase-1-binding protein antibody, TNKS1BP1 antibody, LOC100625088 antibody, Tnks1bp1 antibody
    Background
    TNKS-1 mRNA in urine sediment from patients with bladder TCC correlated with tumor stage, and higher preoperative levels were associated with increased risk of early recurrence. Tankyrase-1 is required in the assembly of bipolar spindles and the spindle-pole protein NuMA as a substrate for covalent modification by tankyrase-1. Data also show that tankyrase 1 inhibition in human cancer cells enhances telomere shortening by a telomerase inhibitor and hastens cell death.
    Alias Symbols: FLJ45975, KIAA1741, TAB182
    Protein Interaction Partner: UBC, RNF219, SPC25, RABGEF1, DCTN3, SPTBN1, NLK, CSNK2A1, CNOT6L, CNOT6, VCP, HNRNPK, DYNC1H1, CBX3, SIRT7, TSG101, Cnot3, Capza1, TNKS2, TNKS,
    Protein Size: 1729
    Molecular Weight
    190 kDa
    Gene ID
    85456
    NCBI Accession
    NM_033396, NP_203754
    UniProt
    Q9C0C2
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