CAPZB antibody (C-Term)

Catalog No. ABIN2787680

Product Details anti-CAPZB Antibody

Target: CAPZB (Capping Protein (Actin Filament) Muscle Z-Line, beta (CAPZB))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPZB antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VEDMENKIRS TLNEIYFGKT KDIVNGLRSV QTFADKSKQE ALKNDLVEAL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against Capzb. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Rat Capzb

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 272 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CAPZB

Target: CAPZB (Capping Protein (Actin Filament) Muscle Z-Line, beta (CAPZB))

Alternative Name: Capzb (CAPZB Products)

Synonyms: CAPB antibody, CAPPB antibody, CAPZ antibody, wu:fk65f06 antibody, zgc:66149 antibody, MGC52754 antibody, capzb antibody, 1700120C01Rik antibody, AI325129 antibody, CPB1 antibody, CPB2 antibody, CPbeat2 antibody, CPbeta1 antibody, CPbeta2 antibody, Cappb1 antibody, capping actin protein of muscle Z-line beta subunit antibody, capping protein (actin filament) muscle Z-line, beta antibody, F-actin-capping protein subunit beta antibody, f-actin-capping protein subunit beta antibody, capping protein (actin filament) muscle Z-line, beta L homeolog antibody, CAPZB antibody, capzb antibody, AOR_1_1412174 antibody, MCYG_05913 antibody, VDBG_04956 antibody, MGYG_06053 antibody, PGTG_03178 antibody, Tsp_07516 antibody, capzb.L antibody, Capzb antibody

Background: F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization.
Alias Symbols: MGC95097
Protein Interaction Partner: Ubc, Dab1,
Protein Size: 272

Molecular Weight: 29 kDa

Gene ID: 298584

NCBI Accession: NM_001005903, NP_001005903

UniProt: Q5XI32

Pathways: Regulation of Actin Filament Polymerization