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IVD antibody (N-Term)
IVD
Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Rabbit
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IVD Antibody
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Target
See all IVD Antibodies
IVD
(Isovaleryl-CoA Dehydrogenase (IVD))
Binding Specificity
All epitopes for IVD antibodies
N-Term
Reactivity
All reactivities for IVD antibodies
Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Rabbit
Host
All hosts for IVD antibodies
Rabbit
Clonality
All clonalities for IVD antibodies
Polyclonal
Conjugate
All conjugates for IVD antibodies
This IVD antibody is un-conjugated
Application
All applications for IVD antibodies
Western Blotting (WB)
Sequence
APKAQEIDRS NEFKNLREFW KQLGNLGVLG ITAPVQYGGS GLGYLEHVLV
Predicted Reactivity
Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 86%
Characteristics
This is a rabbit polyclonal antibody against IVD. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human IVD
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for IVD
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Target
IVD
(Isovaleryl-CoA Dehydrogenase (IVD))
Alternative Name
IVD (IVD Products )
Synonyms
1300016K07Rik antibody, 6720455E18Rik antibody, AI463340 antibody, ACAD2 antibody, ATIVD antibody, ISOVALERYL-COA-DEHYDROGENASE antibody, ISOVALERYL-COA-DEHYDROGENASE PRECURSOR antibody, IVDH antibody, isovaleryl-CoA-dehydrogenase antibody, isovaleryl coenzyme A dehydrogenase antibody, isovaleryl-CoA dehydrogenase antibody, isovaleryl-CoA-dehydrogenase antibody, Ivd antibody, IVD antibody
Background
Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Protein Interaction Partner: SUMO2, UBC, SUMO1, NEDD8, TERF2, IVD, Protein Size: 423
Molecular Weight
46 kDa
Gene ID
3712
UniProt
P26440
Pathways
Monocarboxylic Acid Catabolic Process
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