LRP1 antibody (Middle Region)

Catalog No. ABIN2787741

This Rabbit Polyclonal antibody specifically detects LRP1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Pig, Cow and Dog.

Quick Overview for LRP1 antibody (Middle Region) (ABIN2787741)

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Reactivity: Human, Mouse, Rat, Rabbit, Pig, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LRP1 Antibody

Binding Specificity: Middle Region

Sequence: ATYLSGAQVS TITPTSTRQT TAMDFSYANE TVCWVHVGDS AAQTQLKCAR

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against LRP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LRP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 439 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LRP1

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Alternative Name: LRP1

Background: Low-density lipoprotein receptor-related protein 1 (.-2-macroglobulin receptor, LRP1) is a multifunctional endocytic receptor with an important role in regulating the activity of proteinases in the extracellular matrix. It is also involved in intracellular signaling and the subcellular translocation of preassembled signaling complexes from the plasma membrane.
Alias Symbols: APR, LRP, A2MR, CD91, APOER, TGFBR5, IGFBP3R
Protein Interaction Partner: UBC, COPS5, APP, RANBP9, SKIL, CHFR, CUBN, FBXO6, ANKS1B, RIC8B, PID1, CC2D1A, MAPRE1, HNRNPDL, MAPK8IP1, SNRNP70, APOE, CACNA1A, USP3, CAV1, MMP14, SHC1, MMP13, SERPINA1, F9, F8, LPL, HSP90B1, SRC, PDGFB, THBS1, SCN3A, PLAUR, PLAT, SERPINE1, MDK, LIPC, L
Protein Size: 439

Molecular Weight: 48 kDa

Gene ID: 4035

NCBI Accession: NM_002332

UniProt: Q07954

Pathways: Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling