Beclin 1 antibody (N-Term)

Catalog No. ABIN2787756

This Rabbit Polyclonal antibody specifically detects Beclin 1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Pig, Dog, Rabbit, Cow and Horse.

Quick Overview for Beclin 1 antibody (N-Term) (ABIN2787756)

Target: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Reactivity: Human, Mouse, Rat, Pig, Dog, Rabbit, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Beclin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Beclin 1 Antibody

Binding Specificity: N-Term

Purpose: BECN1 Antibody - N-terminal region

Sequence: MVRMVPVLLS LLLLLGPAVP QENQDGRYSL TYIYTGLSKH VEDVPAFQAL

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 79%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against BECN1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BECN1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58595-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Beclin 1

Target: Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Alternative Name: BECN1

Background:

Background Information: BECN1 plays a central role in autophagy. BECN1 may play a role in antiviral host defense. BECN1 protects against infection by a neurovirulent strain of Sindbis virus.

Gene Name: Beclin 1, autophagy related

Alternative Symbols: ATG6, VPS30, beclin1

Protein Name: Beclin-1

Molecular Weight: 50kDa

Gene ID: 8678

NCBI Accession: NP_003757

UniProt: Q14457

Pathways: Autophagy