Calreticulin 3 antibody (N-Term)

Catalog No. ABIN2787759

This Rabbit Polyclonal antibody specifically detects Calreticulin 3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit and Cow.

Quick Overview for Calreticulin 3 antibody (N-Term) (ABIN2787759)

Target: Calreticulin 3 (CALR3)

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calreticulin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Calreticulin 3 Antibody

Binding Specificity: N-Term

Sequence: MAGPQQQPPY LHLAELTASQ FLEIWKHFDA DGNGYIEGKE LENFFQELEK

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 93%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against CALR3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CALR3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 384 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Calreticulin 3

Target: Calreticulin 3 (CALR3)

Alternative Name: CALR3

Background: Calreticulins, such as CALR3, are Ca(2+)-binding chaperones localized mainly in the endoplasmic/sarcoplasmic reticulum.Calreticulins, such as CALR3, are Ca(2+)-binding chaperones localized mainly in the endoplasmic/sarcoplasmic reticulum Persson et al. (2002) [PubMed 12384296].[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-4 BC014595.2 1-4 5-443 DB459545.1 7-445 444-528 BP370084.1 424-508 529-1034 BC014595.2 529-1034 1035-1035 AC008764.9 27895-27895 c 1036-1273 BC014595.2 1036-1273 1274-1285 DB510196.1 313-324
Alias Symbols: CRT2, FLJ25355, MGC26577, CT93, CMH19
Protein Interaction Partner: SRRM2,
Protein Size: 384

Molecular Weight: 42 kDa

Gene ID: 125972

NCBI Accession: NM_145046, NP_659483

UniProt: Q96L12

Pathways: Activation of Innate immune Response