Calreticulin 3 antibody

Catalog No. ABIN7227580

This Rabbit Polyclonal antibody specifically detects Calreticulin 3 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Calreticulin 3 antibody (ABIN7227580)

Target: Calreticulin 3 (CALR3)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calreticulin 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Calreticulin 3 Antibody

Purpose: Rabbit Anti-CALR3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CALR3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CALR3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Calreticulin 3

Target: Calreticulin 3 (CALR3)

Alternative Name: CALR3

Background: Calreticulin-3, Calreticulin-2, CalsperinCALR3 (Calreticulin 3) is a Protein Coding gene. This protein is also localized to the endoplasmic reticulum lumen, however, its capacity for calcium-binding may be absent or much lower than other family members. This gene is specifically expressed in the testis, and may be required for sperm fertility. Mutation in this gene has been associated with familial hypertrophic cardiomyopathy.

Molecular Weight: 42kD

Gene ID: 125972

UniProt: Q96L12

Pathways: Activation of Innate immune Response