Dematin antibody (C-Term)

Catalog No. ABIN2787795

The Rabbit Polyclonal anti-Dematin antibody (ABIN2787795) specifically detects Dematin in WB. The antibody is reactive with Human, Mouse, Cow, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for Dematin antibody (C-Term) (ABIN2787795)

Target: Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))

Reactivity: Human, Mouse, Cow, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dematin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Dematin Antibody

Binding Specificity: C-Term

Sequence: KGRTKLPPGV DRMRLERHLS AEDFSRVFAM SPEEFGKLAL WKRNELKKKA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against DMTN. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DMTN

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Dematin

Target: Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))

Alternative Name: DMTN

Background: Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation.
Protein Interaction Partner: GOLGA2, YWHAB, APP, NEDD4L, SNCA, PTOV1, DYNC1LI2, PRKACA, SNRPD2, PROCR, SPTB, EPB42, ACTB, ACTC1, DISC1,
Protein Size: 383

Molecular Weight: 42 kDa

Gene ID: 2039

Pathways: Regulation of Actin Filament Polymerization