IMPA1 antibody (Middle Region)

Catalog No. ABIN2787799

The Rabbit Polyclonal anti-IMPA1 antibody is suitable to detect IMPA1 in samples from Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Horse and Pig. It has been validated for WB.

Quick Overview for IMPA1 antibody (Middle Region) (ABIN2787799)

Target: IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IMPA1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IMPA1 Antibody

Binding Specificity: Middle Region

Purpose: IMPA1 Antibody - middle region

Sequence: IVTEAGGVLM DVTGGPFDLM SRRVIAANNR ILAERIAKEI QVIPLQRDDE

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 85%, Pig: 93%, Rabbit: 79%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against IMPA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IMPA1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58713-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for IMPA1

Target: IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))

Alternative Name: IMPA1

Background:

Background Information: IMPA1 is responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. IMPA1 can use myo-inositol monophosphates, myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates.

Gene Name: Inositol(myo)-1(or 4)-monophosphatase 1

Alternative Symbols: IMP, IMPA, MRT59

Protein Name: Inositol monophosphatase 1

Molecular Weight: 30kDa

Gene ID: 3612

NCBI Accession: NP_005527

UniProt: P29218