BMP6 antibody (N-Term)

Catalog No. ABIN2787814

The Rabbit Polyclonal anti-BMP6 antibody is suitable to detect BMP6 in samples from Human, Rat, Mouse, Cow and Pig. It has been validated for WB.

Quick Overview for BMP6 antibody (N-Term) (ABIN2787814)

Target: BMP6 (Bone Morphogenetic Protein 6 (BMP6))

Reactivity: Human, Rat, Mouse, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BMP6 Antibody

Binding Specificity: N-Term

Purpose: BMP6 Antibody - N-terminal region

Sequence: DGGSPGRTEQ PPPSPQSSSG FLYRRLKTQE KREMQKEILS VLGLPHRPRP

Predicted Reactivity: Cow: 77%, Human: 100%, Mouse: 83%, Pig: 85%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against BMP6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BMP6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58756-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BMP6

Target: BMP6 (Bone Morphogenetic Protein 6 (BMP6))

Alternative Name: BMP6

Background:

Background Information: The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

Gene Name: Bone morphogenetic protein 6

Alternative Symbols: VGR, VGR1

Protein Name: Bone morphogenetic protein 6

Molecular Weight: 57kDa

Gene ID: 654

NCBI Accession: NP_001709

UniProt: P22004

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process