SHB antibody (N-Term)

Catalog No. ABIN2787817

The Rabbit Polyclonal anti-SHB antibody is suitable to detect SHB in samples from Human, Mouse, Rat, Cow, Rabbit, Dog and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for SHB antibody (N-Term) (ABIN2787817)

Target: SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SHB Antibody

Binding Specificity: N-Term

Sequence: MAKWLNKYFS LGNSKTKSPP QPPRPDYREQ RRRGERPSQP PQAVPQASSA

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%

Characteristics: This is a rabbit polyclonal antibody against SHB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SHB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 509 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SHB

Target: SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))

Alternative Name: SHB

Background: SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a rol
Alias Symbols: RP11-3J10.8, bA3J10.2
Protein Interaction Partner: SLC39A1, GRAP2, LAT, LCP2, EPS8, JAK3, IL2RG, KDR, SRC, ZAP70, PDGFRA, PLCG1, PIK3R1, VAV1, CRK, JAK1, IL2RB, GRB2, FGFR1, PDGFRB,
Protein Size: 509

Molecular Weight: 55 kDa

Gene ID: 6461

NCBI Accession: NM_003028, NP_003019

UniProt: Q15464