WNT3A antibody (N-Term)

Catalog No. ABIN2787841

There is 1 publication for this product available. The Rabbit Polyclonal anti-WNT3A antibody is suitable to detect WNT3A in samples from Human, Mouse, Rat, Cow, Pig, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Dog and Horse. It has been validated for WB and IHC.

Quick Overview for WNT3A antibody (N-Term) (ABIN2787841)

Target: WNT3A (Wingless-Type MMTV Integration Site Family, Member 3A (WNT3A))

Reactivity: Human, Mouse, Rat, Cow, Pig, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNT3A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-WNT3A Antibody

Binding Specificity: N-Term

Purpose: WNT3A Antibody - N-terminal region

Sequence: MAPLGYFLLL CSLKQALGSY PIWWSLAVGP QYSSLGSQPI LCASIPGLVP

Predicted Reactivity: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 79%, Rat: 86%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against WNT3A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human WNT3A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58818-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-WNT3A antibody (ABIN2787841)

Chiquet, Blanton, Burt, Ma, Stal, Mulliken, Hecht: "Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate." in: Human molecular genetics, Vol. 17, Issue 14, pp. 2212-8, (2008) (PubMed).

Target Details for WNT3A

Target: WNT3A (Wingless-Type MMTV Integration Site Family, Member 3A (WNT3A))

Alternative Name: WNT3A

Background:

Background Information: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryog

Gene Name: Wingless-type MMTV integration site family, member 3A

Alternative Symbols: MGC119418, MGC119419, MGC119420

Protein Name: Protein Wnt-3a

Molecular Weight: 39 kDa

Gene ID: 89780

NCBI Accession: NP_149122

UniProt: P56704

Pathways: WNT Signaling, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity