APOL1 antibody (N-Term)

Catalog No. ABIN2787851

The Rabbit Polyclonal anti-APOL1 antibody is suitable to detect APOL1 in samples from Human. It has been validated for WB.

Quick Overview for APOL1 antibody (N-Term) (ABIN2787851)

Target: APOL1 (Apolipoprotein L, 1 (APOL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-APOL1 Antibody

Binding Specificity: N-Term

Purpose: APOL1 Antibody - N-terminal region

Sequence: AIKYFKEKVS TQNLLLLLTD NEAWNGFVAA AELPRNEADE LRKALDNLAR

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against APOL1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58856-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for APOL1

Target: APOL1 (Apolipoprotein L, 1 (APOL1))

Alternative Name: APOL1

Background:

Background Information: This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.

Gene Name: Apolipoprotein L, 1

Alternative Symbols: APOL, APO-L, FSGS4, APOL-I

Protein Name: Apolipoprotein L1

Molecular Weight: 44kDa

Gene ID: 8542

NCBI Accession: NP_003652

UniProt: O14791