GABARAP antibody (C-Term)

Catalog No. ABIN2787872

This Rabbit Polyclonal antibody specifically detects GABARAP in WB. It exhibits reactivity toward Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Pig and Rabbit.

Quick Overview for GABARAP antibody (C-Term) (ABIN2787872)

Target: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABARAP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GABARAP Antibody

Binding Specificity: C-Term

Purpose: GABARAP Antibody - C-terminal region

Sequence: IHLRAEDALF FFVNNVIPPT SATMGQLYQE HHEEDFFLYI AYSDESVYGL

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against GABARAP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GABARAP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58902-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABARAP

Target: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Alternative Name: GABARAP

Background:

Background Information: Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. GABA(A) receptor-associated protein (GABARAP) is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton.

Gene Name: GABA(A) receptor-associated protein

Alternative Symbols: MM46, ATG8A, GABARAP-a

Protein Name: Gamma-aminobutyric acid receptor-associated protein

Molecular Weight: 14kDa

Gene ID: 11337

NCBI Accession: NP_009209

UniProt: O95166

Pathways: Autophagy