Rubicon antibody (Middle Region)

Catalog No. ABIN2787888

This Rabbit Polyclonal antibody specifically detects Rubicon in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig and Rabbit.

Quick Overview for Rubicon antibody (Middle Region) (ABIN2787888)

Target: Rubicon (KIAA0226) (KIAA0226)

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Rubicon antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Rubicon Antibody

Binding Specificity: Middle Region

Sequence: DQEGGGESQL SSVLRRSSFS EGQTLTVTSG AKKSHIRSHS DTSIASRGAP

Predicted Reactivity: Cow: 85%, Dog: 85%, Guinea Pig: 92%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against KIAA0226. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KIAA0226

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 927 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Rubicon

Target: Rubicon (KIAA0226) (KIAA0226)

Alternative Name: KIAA0226

Background: KIAA0226 negatively regulates endocytic trafficking. KIAA0226 impairs the autophagosome maturation process.KIAA0226 may inhibit PIK3C3 activity.
Alias Symbols: RUBICON
Protein Interaction Partner: BECN1, PIK3C3, EXOC8, EXOC2, EXOC1, PIK3R4, UVRAG, YWHAE, SMAD9,
Protein Size: 927

Molecular Weight: 103 kDa

Gene ID: 9711

NCBI Accession: NM_001145642, NP_001139114

Pathways: Autophagy