VEGFB antibody (Middle Region)

Catalog No. ABIN2787899

The Rabbit Polyclonal anti-VEGFB antibody (ABIN2787899) specifically detects VEGFB in WB. The antibody is reactive with Human, Rat, Mouse, Cow, Dog, Pig and Horse samples.

Quick Overview for VEGFB antibody (Middle Region) (ABIN2787899)

Target: VEGFB (Vascular Endothelial Growth Factor B (VEGFB))

Reactivity: Human, Rat, Mouse, Cow, Dog, Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VEGFB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-VEGFB Antibody

Binding Specificity: Middle Region

Sequence: PTGQHQVRMQ ILMIRYPSSQ LGEMSLEEHS QCECRPKKKD SAVKPDRAAT

Predicted Reactivity: Cow: 87%, Dog: 80%, Horse: 92%, Human: 100%, Mouse: 93%, Pig: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against VEGFB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human VEGFB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 207 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for VEGFB

Target: VEGFB (Vascular Endothelial Growth Factor B (VEGFB))

Alternative Name: VEGFB

Background: Vascular endothelial growth factor B (VEGFB) signals via the endothelial receptor VEGFR1 (MIM 165070) and is a regulator of blood vessel physiology, with a role in endothelial targeting of lipids to peripheral tissues (summarized by Hagberg et al., 2010 [PubMed 20228789]).
Alias Symbols: VEGFL, VRF
Protein Interaction Partner: KLHL12, ADRB2, NRP1, VEGFB, TNXB, VEGFA, FLT1,
Protein Size: 207

Molecular Weight: 21 kDa

Gene ID: 7423

NCBI Accession: NM_003377, NP_003368

UniProt: P49765

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals