ICAM1 antibody (N-Term)

Catalog No. ABIN2787947

This anti-ICAM1 antibody is a Rabbit Polyclonal antibody detecting ICAM1 in WB. Suitable for Human and Rabbit.

Quick Overview for ICAM1 antibody (N-Term) (ABIN2787947)

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reactivity: Human, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICAM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ICAM1 Antibody

Binding Specificity: N-Term

Sequence: LLPGNNRKVY ELSNVQEDSQ PMCYSNCPDG QSTAKTFLTV YWTPERVELA

Predicted Reactivity: Human: 100%, Rabbit: 82%

Characteristics: This is a rabbit polyclonal antibody against ICAM1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ICAM1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 532 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ICAM1

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Alternative Name: ICAM1

Background: This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.
Alias Symbols: BB2, CD54, P3.58, ICAM-1, ICAM1
Protein Interaction Partner: UBC, EGFR, RPL9, RPL26, RPL24, RPL23A, RPL22, RPL19, RPL18, RPL17, RPL13, RPL12, RPL11, EIF3CL, RPS26P11, HIST2H2BF, HIST1H2BA, HNRNPA3, TUBB, HIST2H3C, HIST1H2BK, TUBB6, TUBB7P, EIF3L, TUBE1, RPL26L1, YBX2, EIF3K, LSM3, PABPC1, RPL36, RPL13A, RPL35, SUPT
Protein Size: 532

Molecular Weight: 59 kDa

Gene ID: 3383

NCBI Accession: NM_000201, NP_000192

UniProt: P05362

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling