VCP antibody (C-Term)

Catalog No. ABIN2788042

The Rabbit Polyclonal anti-VCP antibody has been validated for WB, IHC, IP. It is suitable to detect VCP in samples from Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig.

Quick Overview for VCP antibody (C-Term) (ABIN2788042)

Target: VCP (Valosin Containing Protein (VCP))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VCP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-VCP Antibody

Binding Specificity: C-Term

Sequence: EMFAQTLQQS RGFGSFRFPS GNQGGAGPSQ GSGGGTGGSV YTEDNDDDLY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against VCP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human VCP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 806 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for VCP

Target: VCP (Valosin Containing Protein (VCP))

Alternative Name: VCP

Background: The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.
Alias Symbols: IBMPFD, MGC131997, MGC148092, MGC8560, TERA, p97, ALS14
Protein Interaction Partner: AMFR, UBXN2B, CEP19, FAM104A, UBC, ATXN3, FUS, DTNB, WDYHV1, VCP, LNX1, PSMA1, UBXN1, ASPSCR1, NSFL1C, RPL9, UBOX5, HUWE1, ISG15, ATG5, PLAA, RNF8, YOD1, VAPA, RPL23, GTF3C5, ACTB, PPP3CA, PPM1B, PHKG2, MDM2, CDK2, CCNB1, AR, OTU1, TUBB, UBXN2A, H2AFV, FB
Protein Size: 806

Molecular Weight: 89 kDa

Gene ID: 7415

NCBI Accession: NM_007126, NP_009057

UniProt: P55072

Pathways: ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway