UBL4A antibody (Middle Region)

Catalog No. ABIN2788049

This Rabbit Polyclonal antibody specifically detects UBL4A in WB. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Dog, Horse and Saccharomyces cerevisiae.

Quick Overview for UBL4A antibody (Middle Region) (ABIN2788049)

Target: UBL4A (Ubiquitin-Like 4A (UBL4A))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Dog, Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBL4A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UBL4A Antibody

Binding Specificity: Middle Region

Purpose: UBL4A Antibody - middle region

Sequence: EGEAQRLADS PPPQVWQLIS KVLARHFSAA DASRVLEQLQ RDYERSLSRL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Yeast: 83%

Characteristics: This is a rabbit polyclonal antibody against UBL4A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UBL4A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59392-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for UBL4A

Target: UBL4A (Ubiquitin-Like 4A (UBL4A))

Alternative Name: UBL4A

Background:

Background Information: UBL4A is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. UBL4A is the TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.

Gene Name: Ubiquitin-like 4A

Alternative Symbols: GDX, G6PD, GET5, MDY2, UBL4, TMA24, DX254E, DXS254E

Protein Name: Ubiquitin-like protein 4A

Molecular Weight: 18kDa

Gene ID: 8266

NCBI Accession: NP_055050

UniProt: B7NZQ9

Pathways: Ubiquitin Proteasome Pathway