UBL4A antibody (C-Term)

Catalog No. ABIN2788050

Product Details anti-UBL4A Antibody

Target: UBL4A (Ubiquitin-Like 4A (UBL4A))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBL4A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SAADASRVLE QLQRDYERSL SRLTLDDIER LASRFLHPEV TETMEKGFSK

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 92%, Human: 100%, Mouse: 86%, Pig: 92%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against UBL4A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human UBL4A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 157 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UBL4A

Target: UBL4A (Ubiquitin-Like 4A (UBL4A))

Alternative Name: UBL4A (UBL4A Products)

Synonyms: DX254E antibody, DXS254E antibody, G6PD antibody, GDX antibody, GET5 antibody, MDY2 antibody, TMA24 antibody, UBL4 antibody, DXHXS254E antibody, DXS254Eh antibody, Gdx antibody, Ubl4a antibody, MGC128599 antibody, gdx antibody, g6pd antibody, ubl4 antibody, dx254e antibody, dxs254e antibody, RGD1563983 antibody, Ubl4 antibody, ubl4a antibody, Slc10a3 antibody, ubiquitin like 4A antibody, ubiquitin-like 4A antibody, ubiquitin like 4A S homeolog antibody, zgc:56596 antibody, ubiquitin-like protein 4A antibody, UBL4A antibody, Ubl4a antibody, ubl4a antibody, ubl4a.S antibody, zgc:56596 antibody, LOC100723318 antibody

Background: UBL4A is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. UBL4A is the TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.
Alias Symbols: DX254E, DXS254E, G6PD, GDX, UBL4, GET5, MDY2, TMA24
Protein Interaction Partner: MEOX2, HUWE1, TRAF4, CDCA7L, FAF1, VAPB, SGTA, SHFM1, UBC, CDK18, HIPK4, FAF2, UQCRC1, UBE2G2, UBA52, GET4, RAB14, PTPLAD1, CD320, HSD17B12, GEMIN4, UBQLN1, PABPC1, FAM162A, PRPF31, GEMIN5, METTL21B, RPL36, CORO1C, RPL13A, PHB2, DDX20, ERLIN2, RER1, RAB35
Protein Size: 157

Molecular Weight: 18 kDa

Gene ID: 8266

NCBI Accession: NM_014235, NP_055050

UniProt: B7NZQ9

Pathways: Ubiquitin Proteasome Pathway