MLF1IP antibody (N-Term)

Catalog No. ABIN2788059

This Rabbit Polyclonal antibody specifically detects MLF1IP in WB. It exhibits reactivity toward Human, Cow, Horse and Pig.

Quick Overview for MLF1IP antibody (N-Term) (ABIN2788059)

Target: MLF1IP (MLF1 Interacting Protein (MLF1IP))

Reactivity: Human, Cow, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLF1IP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MLF1IP Antibody

Binding Specificity: N-Term

Purpose: CENPU Antibody - N-terminal region

Sequence: IYADEEEFSK HCGLSLSSTP PGKEAKRSSD TSGNEASEIE SVKISAKKPG

Predicted Reactivity: Cow: 86%, Horse: 79%, Human: 100%, Pig: 79%

Characteristics: This is a rabbit polyclonal antibody against MLF1IP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human CENPU

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59412-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MLF1IP

Target: MLF1IP (MLF1 Interacting Protein (MLF1IP))

Alternative Name: CENPU

Background:

Background Information: The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008]

Gene Name: centromere protein U

Alternative Symbols: KLIP1, PBIP1, CENP50, MLF1IP, CENPU50

Protein Name: centromere protein U

Molecular Weight: 35kDa

Gene ID: 79682

NCBI Accession: NP_078905

UniProt: Q71F23