SYT1 antibody (Middle Region)

Catalog No. ABIN2788072

The Rabbit Polyclonal anti-SYT1 antibody has been validated for WB and IHC. It is suitable to detect SYT1 in samples from Human, Rat, Mouse, Cow, Rabbit, Dog, Horse, Zebrafish (Danio rerio) and Guinea Pig.

Quick Overview for SYT1 antibody (Middle Region) (ABIN2788072)

Target: SYT1 (Synaptotagmin I (SYT1))

Reactivity: Human, Rat, Mouse, Cow, Rabbit, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SYT1 Antibody

Binding Specificity: Middle Region

Sequence: FDRFSKHDII GEFKVPMNTV DFGHVTEEWR DLQSAEKEEQ EKLGDICFSL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Syt1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 421 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SYT1

Target: SYT1 (Synaptotagmin I (SYT1))

Alternative Name: Syt1

Background: Syt1 may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner, these are neurexins, syntaxin and AP2.
Alias Symbols: AW124717, G630098F17Rik, SytI
Protein Interaction Partner: Lrp1b, CALM1, Syp, Htt,
Protein Size: 421

Molecular Weight: 47 kDa

Gene ID: 20979

NCBI Accession: NM_009306, NP_033332

UniProt: P46096

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport