DOC2B antibody (C-Term)

Catalog No. ABIN2788095

The Rabbit Polyclonal anti-DOC2B antibody is suitable to detect DOC2B in samples from Human, Rat, Mouse, Zebrafish (Danio rerio), Rabbit, Horse, Guinea Pig, Dog and Cow. It has been validated for WB.

Quick Overview for DOC2B antibody (C-Term) (ABIN2788095)

Target: DOC2B (Double C2-Like Domains, beta (DOC2B))

Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Rabbit, Horse, Guinea Pig, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOC2B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DOC2B Antibody

Binding Specificity: C-Term

Purpose: DOC2B Antibody - C-terminal region

Sequence: VWDYDIGKSN DYIGGCQLGI SAKGERLKHW YECLKNKDKK IERWHQLQNE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against RPH3A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human DOC2B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59505-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DOC2B

Target: DOC2B (Double C2-Like Domains, beta (DOC2B))

Alternative Name: DOC2B

Background:

Background Information: There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes, these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2B is expressed ubiquitously and is suggested to be involved in Ca(2+)-dependent intracellular vesicle trafficking in various types of cells.

Gene Name: double C2-like domains, beta

Alternative Symbols: DOC2BL

Protein Name: double C2-like domain-containing protein beta

Molecular Weight: 38kDa

Gene ID: 8447

NCBI Accession: NP_003576

UniProt: Q14184

Pathways: Positive Regulation of Peptide Hormone Secretion