NCKIPSD antibody (Middle Region)

Catalog No. ABIN2788096

The Rabbit Polyclonal anti-NCKIPSD antibody has been validated for WB. It is suitable to detect NCKIPSD in samples from Human, Mouse, Rat, Guinea Pig, Cow and Dog.

Quick Overview for NCKIPSD antibody (Middle Region) (ABIN2788096)

Target: NCKIPSD (NCK Interacting Protein with SH3 Domain (NCKIPSD))

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCKIPSD antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NCKIPSD Antibody

Binding Specificity: Middle Region

Sequence: LVSSVLPVEL ARDMQTDTQD HQKLCYSALI LAMVFSMGEA VPYAHYEHLG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NCKIPSD. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NCKIPSD

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 715 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NCKIPSD

Target: NCKIPSD (NCK Interacting Protein with SH3 Domain (NCKIPSD))

Alternative Name: NCKIPSD

Background: The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3,11)(p21,q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified.
Alias Symbols: AF3P21, DIP, DIP1, MGC23891, ORF1, SPIN90, WASLBP, WISH
Protein Interaction Partner: SORBS3, PSMD9, YWHAB, UBC, GRB2, CRK, FASLG, KHDRBS1, STAC, DMRTB1, ARHGEF7, BAIAP2, YWHAG, NCK2, DLG4, MAPK3, NCK1, WAS, DIAPH2, ITGB1, DIAPH3,
Protein Size: 715

Molecular Weight: 79 kDa

Gene ID: 51517

NCBI Accession: NM_184231, NP_909119

UniProt: Q9NZQ3

Pathways: Protein targeting to Nucleus