Gastrin-Releasing Peptide antibody (C-Term)

Catalog No. ABIN2788114

This Rabbit Polyclonal antibody specifically detects Gastrin-Releasing Peptide in WB. It exhibits reactivity toward Human.

Quick Overview for Gastrin-Releasing Peptide antibody (C-Term) (ABIN2788114)

Target: Gastrin-Releasing Peptide (GRP)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Gastrin-Releasing Peptide antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Gastrin-Releasing Peptide Antibody

Binding Specificity: C-Term

Purpose: GRP Antibody - C-terminal region

Sequence: ENRNHQPPQP KALGNQQPSW DSEDSSNFKD VGSKGKGSQR EGRNPQLNQQ

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against GRP. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59548-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Gastrin-Releasing Peptide

Target: Gastrin-Releasing Peptide (GRP)

Alternative Name: GRP

Background:

Background Information: This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Name: Gastrin-releasing peptide

Alternative Symbols: BN, GRP-10, proGRP, preproGRP

Protein Name: Gastrin-releasing peptide

Molecular Weight: 15kDa

Gene ID: 2922

NCBI Accession: NP_001012530

UniProt: P07492

Pathways: Peptide Hormone Metabolism, Hormone Activity