Clarin 1 antibody (C-Term)

Catalog No. ABIN2788125

The Rabbit Polyclonal anti-Clarin 1 antibody (ABIN2788125) specifically detects Clarin 1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig and Horse samples.

Quick Overview for Clarin 1 antibody (C-Term) (ABIN2788125)

Target: Clarin 1 (CLRN1)

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Clarin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Clarin 1 Antibody

Binding Specificity: C-Term

Purpose: CLRN1 Antibody - C-terminal region

Sequence: QSEKYTTSFW VIFFCFFVHF LNGLLIRLAG FQFPFAKSKD AETTNVAADL

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against CLRN1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLRN1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59580-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Clarin 1

Target: Clarin 1 (CLRN1)

Alternative Name: CLRN1

Background:

Background Information: This gene encodes a protein that contains a cytosolic N-terminus, multiple helical transmembrane domains, and an endoplasmic reticulum membrane retention signal, TKGH, in the C-terminus. The encoded protein may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIIa. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Gene Name: Clarin 1

Alternative Symbols: RP61, USH3, USH3A

Protein Name: Clarin-1

Molecular Weight: 26kDa

Gene ID: 7401

NCBI Accession: NP_777367

UniProt: P58418