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SPR antibody (C-Term)

SPR Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2788144
  • Target See all SPR Antibodies
    SPR (Sepiapterin Reductase (SPR))
    Binding Specificity
    • 15
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat, Dog, Horse, Rabbit
    Host
    • 42
    • 10
    Rabbit
    Clonality
    • 45
    • 7
    Polyclonal
    Conjugate
    • 28
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPR antibody is un-conjugated
    Application
    • 51
    • 23
    • 13
    • 13
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    ETSVDPDMRK GLQELKAKGK LVDCKVSAQK LLSLLEKDEF KSGAHVDFYD
    Predicted Reactivity
    Dog: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 79%
    Characteristics
    This is a rabbit polyclonal antibody against SPR. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human SPR
    Top Product
    Discover our top product SPR Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 261 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SPR (Sepiapterin Reductase (SPR))
    Alternative Name
    SPR (SPR Products)
    Synonyms
    SDR38C1 antibody, AA409688 antibody, ENSMUSG00000071345 antibody, Gm10328 antibody, CG12117 antibody, Dmel\\CG12117 antibody, SR antibody, sptr antibody, xspr antibody, DDBDRAFT_0188686 antibody, DDBDRAFT_0191275 antibody, DDB_0188686 antibody, DDB_0191275 antibody, zgc:194446 antibody, sepiapterin reductase antibody, Sepiapterin reductase antibody, sepiapterin reductase L homeolog antibody, sepiapterin reductase b antibody, SPR antibody, Spr antibody, Sptr antibody, spr.L antibody, sprE antibody, CpipJ_CPIJ000511 antibody, sr antibody, spr antibody, sprb antibody
    Background
    This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
    Alias Symbols: SDR38C1
    Protein Interaction Partner: UBC, YWHAQ, MRPL53, SRPRB, SUGP1, SBDS, AHCYL1, SCO2, RAD23B, PPM1G, NDUFA2, IDH3G, CRK, ASS1, CAMK2G,
    Protein Size: 261
    Molecular Weight
    28 kDa
    Gene ID
    6697
    NCBI Accession
    NM_003124, NP_003115
    UniProt
    P35270
    Pathways
    Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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