GPR172B antibody (C-Term)

Catalog No. ABIN2788146

The Rabbit Polyclonal anti-GPR172B antibody (ABIN2788146) specifically detects GPR172B in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse and Pig samples.

Quick Overview for GPR172B antibody (C-Term) (ABIN2788146)

Target: GPR172B (G Protein-Coupled Receptor 172B (GPR172B))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR172B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GPR172B Antibody

Binding Specificity: C-Term

Sequence: SLPSVTTGGS GPELQLGSPG AEEEEKEEEE ALPLQEPPSQ AAGTIPGPDP

Predicted Reactivity: Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against SLC52A1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human SLC52A2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GPR172B

Target: GPR172B (G Protein-Coupled Receptor 172B (GPR172B))

Alternative Name: SLC52A1

Background: This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia.
Alias Symbols: PAR1, RFT3, RFVT2, hRFT3, BVVLS2, GPCR41, GPR172A, D15Ertd747e
Protein Size: 350

Molecular Weight: 38 kDa

Gene ID: 79581

NCBI Accession: NM_001253815, NP_001240744

UniProt: Q9HAB3